Authors: Rosenfeldt FL, Haas SJ, Krum H, et al.
Journal: Journal of Human Hypertension. 2007; 21(4): 297-306.
Summary:
This study conducted a meta-analysis of randomized controlled trials investigating the effects of coenzyme Q10 (CoQ10) supplementation on blood pressure in patients with hypertension. The meta-analysis included 12 trials with a total of 362 patients.
Results:
The study found that CoQ10 supplementation significantly reduced both systolic and diastolic blood pressure compared to placebo. The effect was more pronounced in patients with more severe hypertension and with longer duration of treatment. No significant adverse effects were reported.
Conclusion:
The study suggests that CoQ10 supplementation may have beneficial effects on blood pressure in patients with hypertension. However, the optimal dose and duration of treatment, as well as the long-term effects and safety, need to be further investigated.